Local News

Trial shows promise for treating anxiety with LSD

Weather

Ava's Weather Forecast for Saturday, Oct 25: Foggy start to Saturday!

Fact or Fiction

China testing dispensers that release toilet paper after ad is watched?

World News

At United Nations, Zelenskyy warns of global arms race

UK doctors achieve medical first with successful Huntington's disease treatment

National News

Pittsburgh children's hospital sued for allegedly denying gender-affirming care

National News

Your genetics could dictate how well weight loss drugs work

National News

Woman sentenced over 4 years for fraud scheme to try to auction Graceland

Local News

Apartment amenities add hundreds to rent -- are they worth the extra cost?

National Politics

Economy was strength for Trump in first term. Not anymore, according to polling

Local News

San Diego Police: Man shot in City Heights alley, dies

Local News

2 students arrested, accused of bringing BB gun to Spring Valley middle school

National News

Camp Mystic plans to reopen in Texas next summer, a year after floods killed 27

National Politics

Grijalva victory in Arizona helps Democrats retain key border district

Local News

Mountain biker rescued from Otay Lakes Park trail by Border Patrol

National Politics

UN says Trump's team to blame for nonworking escalator and teleprompter

Local News

California awards 4 San Diego County housing developments nearly $60 million

Local News

Father Joe's Villages opens detox facility for San Diego's homeless population

Local News

Deputies investigate report of suspicious person following Lemon Grove student

Padres

O'Hearn's grand slam, Vásquez's 7 shutdown innings help Padres beat Brewers 7-0

National News

1 detainee killed, 2 critically wounded in ICE facility shooting, DHS says

The Streamline

10News Wake Up Call: Kimmel makes return to TV; hunt for San Diego church vandal

National News

Rare hurricane warning issued for the eastern Atlantic’s Azores

Weather

Moses’s Forecast: Cooling off next few days

Entertainment

Jimmy Kimmel returns to ABC; Trump threatens network with legal action

Fact or Fiction

Fact or Fiction: Kimmel praised Roseanne Barr being taken off the air?

Local News

Loved ones speak on sister & friend taken too soon in deadly Carlsbad carjacking

Local News

'Merrill Madness': New mural of Padres' Jackson Merrill unveiled in East Village

Local News

Padres fans rush to buy playoff merchandise

Sports

MLB will use robot umpires in 2026

Weather

Megan's Forecast: Cooling off with a weekend rain chance

Local News

San Diego museum exhibit reveals stories of lost neighborhoods

Celebrating Community

San Diego vineyard brings authentic Spanish wine tradition to California

Local News

San Diego International Airport's new T1 officially opens after $3.8B investment

Local News

Investigators seek public’s help identifying suspect in 2024 Oceanside homicide

National Politics

Pantry staples and easy meals are gaining popularity, grocery data shows

National News

Sandy Hook Promise says hotline helped prevent potential school shooting

Local News

Flight instructor shares moment he watched small plane crash in Fallbrook area

World News

Scientists discover new dinosaur from Argentina with crocodile bone in its mouth

National Politics

Auto loan delinquencies on the rise: Here's what that means for the economy

What doctors say pregnant women need to know for Tylenol, leucovorin and autism

National Politics

Trump says Kyiv can ‘win all of Ukraine back’ amid Russia’s economic struggles

National Politics

Powell signals Federal Reserve to move slowly on interest rate cuts

National News

Hunters found dead in Colorado wilderness were struck by lightning, coroner says

National News

Jury convicts man accused in Trump golf course assassination attempt

Local News

$2,000 reward offered in series of religious hate crimes around San Diego

National News

OB-GYN pushes back on Trump’s Tylenol-autism claims, citing lack of evidence

National Politics

Trump cancels meeting with Democratic leaders as government shutdown looms

National News

'Nightmare bacteria' cases are increasing in the US, CDC study says

National News

Spirit Airlines to furlough 1,800 flight attendants amid second bankruptcy

Measles outbreak worsens along Arizona-Utah border

National News

MacKenzie Scott gives $70 million to UNCF to financially strengthen HBCUs

National Politics

Trump criticizes UN over wars, migration and climate change

Entertainment

Jimmy Kimmel returns to ABC, but you still may not be able to watch his show

Weather

San Diego September 23rd Forecast - A warm first full day of fall!

Local News

1 person dead in officer-involved shooting in City Heights

Local News

CBP officials report $24M in narcotics seized last month

National News

Man accused of Trump golf course assassination attempt to give closing argument

The Streamline

10News Wake Up Call: New era at SD Intl. Airport; warning for apartment hunters

National News

Secret Service halts network posing ‘imminent’ threat to telecom systems

World News

France defies US, Israel in recognizing Palestinian state at UN

National News

West Point accused of suppressing faculty speech in new lawsuit

Local News

First passengers land at new Terminal 1 at San Diego International