San Diego police are investigating a three-car crash near Campanile Drive and Montezuma Road in the College Area.
Emergency crews were dispatched to the wreck just after 8:20 p.m. Wednesday.
One person was taken to the hospital with unknown injuries. Two other people suffered minor injuries, but declined medical attention.
Montezuma Road between 55th Street and College Avenue is closed while police investigate. Campanile Drive at Montezuma is also closed.
The road closures are expected to be in effect for the next couple of hours.