SAN DIEGO (KGTV) -- Two people were killed in a wrong-way crash on Interstate 5 in the downtown San Diego area Wednesday morning.
The crash happened at around 1:15 a.m. on northbound Interstate 5 near the 4th Avenue overpass, according to the California Highway Patrol.
CHP officials said they received a report of a black sedan traveling south on the northbound lanes near Old Town. Moments later, another 911 caller reported the same black car crashed head-on into another vehicle.
Responding emergency crews arrived but were unable to save either driver, officials said. A female driver and a male driver were declared dead at the scene.
It was no immediately determined which driver was traveling south on the northbound lanes.
Due to the crash investigation and clean-up, all northbound I-5 lanes between Hawthorn Street -- towards San Diego's airport -- and state Route 163, were closed for several hours.
Southbound SR-163 transition to northbound I-5, and several surface street on-ramps to I-5 were also shut down.
By 6:20 a.m., tow trucks removed the wreckage and authorities were preparing to reopen all affected lanes.