Wimbledon, England -- (Sports Network) - Second-seeded Serena Williams and third- seeded Venus Williams will square off in Saturday's ladies' final at Wimbledon, where Venus topped her younger sister in last year's third all- Williams finale at the All England Club.

Venus bested her fellow former world No. 1 sibling Serena 7-5, 6-4 in last year's final, as Venus nailed down a second straight and fifth overall Wimbledon title. Saturday will mark the fourth all-Williams Wimbledon final, with Serena holding a 2-1 edge thus far.

Serena and Venus will meet for a 21st time, as the superstar siblings have split their first 20 matchups. Serena is 4-3 when they've met in Grand Slam finals. They've split two matches this year, with Venus winning a semifinal in Dubai and Serena taking a semifinal in Miami.

The 10-time major champion Serena will appear in her 14th career Grand Slam final (10-3). She captured Wimbledon titles in 2002 and 2003 by beating her big sister in finals and was the runner-up here in 2004 and last year.

The 27-year-old Serena owns 33 career singles titles, including this year's Aussie Open crown.

The 29-year-old seven-time major champion Venus, like Serena, will also appear in her 14th Grand Slam final (7-6), including her eighth at the All England Club (5-2). She owns 41 career titles, including ones in Acapulco and Dubai this season.

Venus, who hasn't lost on Centre Court since 2004, has won 35 straight sets at the world's most prestigious tennis event. The tall American is 68-9 all- time on grass overall, including 64-7 at Wimbledon.

The mighty Williams sisters have combined for seven of the last nine Wimbledon titles, and at least one of the sisters has appeared in eight of the last nine championship matches here.

In Thursday's semifinals, Serena outlasted fourth-seeded Russian Elena Dementieva in an epic three-setter and Venus destroyed top-ranked Russian Dinara Safina, dropping only one game in the process on Centre Court.