SAN DIEGO - San Diego police Tuesday investigated a home-invasion robbery in Serra Mesa in which three men targeted a family residence where marijuana was being grown.

The home invasion robbery in the 8500 block of Hulburt Street was reported at 10:53 p.m. Monday, according to San Diego police Officer David Stafford.

Three men armed with handguns entered the home through a rear door and threatened a 45-year-old man, a 45-year-old woman and their 17- and 10-year-old children, Stafford said in a statement.

The gunmen took cash and marijuana before fleeing in an unknown direction, he said, noting all three wore dark clothing and carried backpacks.

"Obviously the occupants were overpowered and overcome with the individuals," said Lt. Paul Rorrison of the San Diego Police Department. "It was a total surprise."

He said the door was unlocked. 

"Apparently three suspects described as black males wearing bandanas and all three armed with handguns forcibly entered the residence and took control of the two adults, the two children were sleeping at the time," Lt. Rorrison said. 

No one was hurt.

10News learned the investigation led police to a Days Inn in the 5300 block of Adobe Falls Road, where two men were taken into custody at around 3:20 a.m. Police cannot confirm if they were the suspects connected to the Serra Mesa incident, but did say the home invasion investigation led them to the area.