Actor-screenwriter Nia Vardalos first turned her one-woman stage show about growing up Greek into "My Big Fat Greek Wedding," the comedy sensation that through an amazing word-of-mouth campaign went on to generate over $241 million at the North American box office.

But even with a best original screenplay Oscar nomination and a film that earned $236 million more than its shooting budget, Vardalos wants you to know that it's not important whether her new film -- the cabaret comedy "Connie and Carla" -- comes even close to making "Greek Wedding's" box office.

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Like Vardalos told me when "Greek Wedding" began to steamroll its way to becoming the biggest comedy romance of all time in 2002, the definition of success for her has -- and always will be -- determined by the emotional response to her material and not dollar signs. And a recent visit by her to talk about "Connie and Carla" with me affirmed that.

"It's about a moment of connectedness with an absolute stranger," Vardalos explained. "It's about when a big burly guy comes up to me on the streets and says, 'I'm just like Toula.' I absolutely love that. I feel like I have more cousins than ever."

So, Vardalos said, she doesn't feel pressure with exceeding the success of "Greek Wedding" with "Connie and Carla" -- she sees opportunity.

"Other people ask, will it do as well? I don't worry about that," Vardalos said. "I've snuck into the sneak preview screenings -- and to see people laughing that hard and applauding, it makes me teary. It's a great feeling."

Inspired by her past as a dinner theater performer, "Connie and Carla" -- opening Friday -- co-stars Toni Collette (who also had a blissful breakout performance, thanks to "Muriel's Wedding) and David Duchovny. See our video coverage of the film throughout the week to get a peek at Vardalos' latest Hollywood adventure.